Basic Information
VIS ID
TVIS44014604
Fusion event
HTLV-1-LOC110467531 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
24183695/24000893 (Hg38)
End
24183695/24000893 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC110467531
Nearest miRNA
hsa-mir-10395/Upstream/3601539; hsa-let-7e/Downstream/11121807;
Nearest TSS
ENST00000633603/Upstream/42963; ENST00000597683/Downstream/32512;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/28936, chr19-CpG: 42/Downstream/3792727
Nearby gene
ZNF254(+32512) ;
Upstream sequence
cagactggcaaagcccttagagcaaattcttaccctgaacttactgatccagcttgctgatttcccttacctacattgttctaacatgccagaggctgtt
Downstream sequence
taccttggagacctgctgtggatatggttacagcctggtgtgagatttacaccctctcccccagattttcaagggcctgtgagagctcaccaggtgcctc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate