Basic Information
VIS ID
TVIS44014628
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
208168843/207304119 (Hg38)
End
208168843/207304119 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/34695; hsa-mir-1244-1/Downstream/450688;
Nearest TSS
ENST00000437798/Upstream/43674; ENST00000414681/Downstream/225618;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/137366, chr2-CpG: 174/Downstream/225112
Nearby gene
MIR1302-4(-34695) ;
Upstream sequence
gaagtattgatacatactacaacatgaatgagctttgaaaacaccatgttaaatgcaagacgctagtcacaaaaggccacatattatatgagtccattta
Downstream sequence
tatgaaatgtccagagtaggcaaatctacaaagacagaaagtaaattagtggttgcttatggctgggagaaatgaggagtaggggagggtgacagctaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate