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TVIS44014632
Basic Information
VIS ID
TVIS44014632
Fusion event
HTLV-1-PMEPA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
56246260/57671204 (Hg38)
End
56246260/57671204 (Hg38)
Orient
+
Location type
Intronic
Target gene
PMEPA1
miRNAs that regulate target gene
hsa-mir-7-5p
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-511-5p
;
hsa-mir-6830-3p
;
hsa-mir-654-3p
;
hsa-mir-487a-3p
;
hsa-mir-154-3p
;
hsa-mir-561-3p
;
hsa-mir-548at-5p
;
hsa-mir-3678-3p
;
hsa-mir-1273h-3p
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-200b-5p
;
hsa-mir-200a-5p
;
hsa-mir-410-3p
;
hsa-mir-5692b
;
hsa-mir-5692c
;
hsa-mir-369-3p
;
hsa-mir-7161-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-367-3p
;
hsa-mir-92a-3p
;
hsa-mir-92b-3p
;
hsa-mir-25-3p
;
hsa-mir-32-5p
;
hsa-mir-363-3p
;
hsa-mir-4279
;
hsa-mir-1229-3p
;
hsa-mir-6749-3p
;
hsa-mir-6845-3p
;
hsa-mir-6756-3p
;
hsa-mir-3127-3p
;
hsa-mir-6777-3p
;
hsa-mir-4639-3p
;
hsa-mir-4656
;
hsa-mir-3616-3p
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-19a-3p
;
hsa-mir-219a-1-3p
;
hsa-mir-3126-5p
;
hsa-mir-3155a
;
hsa-mir-3155b
;
hsa-mir-3909
;
hsa-mir-4438
;
hsa-mir-4712-3p
;
hsa-mir-484
;
hsa-mir-571
;
hsa-mir-6755-3p
;
hsa-mir-6852-3p
;
hsa-mir-6873-5p
;
hsa-mir-6875-5p
;
hsa-mir-760
Nearest miRNA
hsa-mir-103a-2/Upstream/349613; hsa-mir-1-1/Downstream/1146411;
Nearest TSS
ENST00000382410/Upstream/50628;
ENST00000613231/Downstream/19420;
Nearest CpG islands
None/Target,
chr20-CpG: 39/Upstream/6484
,
chr20-CpG: 30/Downstream/989
Upstream sequence
ATCCTTCTTGCTATTATCCAAATGGAAAGAACTAATGGGATTTTTGTTTCTATTGTCACTGACATCGAACACCTTTAAACATCCACTGTCAGCAAAATAT
Downstream sequence
CAGTCACCGTTTGAATTATTGGCAGAACGGAGTGAACTCACAGTGAGCGAGCAGTCAGTGGACATGTCGGAGGTGCATAACATCCGAAAGTTATTTAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL182
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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