Basic Information
VIS ID
TVIS44014646
Fusion event
HTLV-1-LOC284930 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
48202832/47807083 (Hg38)
End
48202832/47807083 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA22A
Target gene
LOC284930
Nearest miRNA
hsa-let-7a-3/Upstream/1693315; hsa-mir-12114/Downstream/467281;
Nearest TSS
ENST00000624155/Upstream/120842; ENST00000449941/Downstream/53588;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/593511, chr22-CpG: 25/Downstream/402262
Upstream sequence
CGGTGCGGCTTTTGGAGGGAATCTCTTCTAATCCCCAAATTGATGACCTCTGGAAGAATGTGAGGGAACTCCGCGATCTCTGCTCTGTAAGAACATGGGC
Downstream sequence
CTCTGTGCCTTGGTTCCTGGCTGGTGCCTGCCTCAGACTTGCTGCCTGGGTTCCCCCGTGTCCCCACTGCTGCCTCTGCATCTCACTGGCATTTCTCAAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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