Basic Information
VIS ID
TVIS44014663
Fusion event
HTLV-1-TBL1XR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.32
Reference genome
End
176803490/177085702 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-122-5p ; hsa-mir-21-5p ; hsa-mir-30c-5p ; hsa-mir-548c-3p ; hsa-mir-5691 ; hsa-mir-6805-3p ; hsa-mir-4433b-5p ; hsa-mir-4427 ; hsa-mir-506-5p ; hsa-mir-3613-3p ; hsa-mir-5003-5p ; hsa-mir-4668-5p ; hsa-mir-625-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-3148 ; hsa-mir-6770-5p ; hsa-mir-3179 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-3154 ; hsa-mir-4314 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-505-5p ; hsa-mir-3194-3p ; hsa-mir-767-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3192-5p ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-1277-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-511-5p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6509-3p ; hsa-mir-4711-3p ; hsa-mir-6830-3p ; hsa-mir-627-3p ; hsa-mir-4742-3p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-181c-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-550b-2-5p ; hsa-mir-4684-5p ; hsa-mir-6886-3p ; hsa-mir-938 ; hsa-mir-942-5p ; hsa-mir-554 ; hsa-mir-5088-3p ; hsa-mir-5579-5p ; hsa-mir-382-5p ; hsa-mir-7150 ; hsa-mir-4433a-5p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-6834-3p ; hsa-mir-186-3p ; hsa-mir-4448 ; hsa-mir-7110-3p ; hsa-mir-6758-3p ; hsa-mir-7705 ; hsa-mir-1278 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-let-7g/Upstream/570551; hsa-mir-1224/Downstream/6801098;
Upstream sequence
actttatgactgaaaaaATATGGGAAAAAATTCTAAGACAATAGGATGTATAGGAAAATGATAGCAAACACTATGATCTTCCTGAATAAGAGATTACATA
Downstream sequence
TAGATGACAATAAAATTCTGTTTTAATAAAAGAAAATTTTCCCAAAATAACAAATATCTTTAGCTCTCAAAAGTAATGAAAAAATCTAGAGACCTGTCAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate