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TVIS44014668
Basic Information
VIS ID
TVIS44014668
Fusion event
HTLV-1-CLOCK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
56366202/55500035 (Hg38)
End
56366202/55500035 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
CLOCK
miRNAs that regulate target gene
hsa-mir-141-3p
;
hsa-mir-182-5p
;
hsa-mir-106b-5p
;
hsa-mir-142-3p
;
hsa-mir-26b-5p
;
hsa-mir-21-5p
;
hsa-mir-124-3p
;
hsa-mir-152-3p
;
hsa-mir-34a-5p
;
hsa-mir-20a-5p
;
hsa-mir-203a-3p
;
hsa-mir-526b-5p
;
hsa-mir-4635
;
hsa-mir-5571-5p
;
hsa-mir-4423-3p
;
hsa-mir-6826-5p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-3622a-5p
;
hsa-mir-5582-5p
;
hsa-mir-552-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-1290
;
hsa-mir-302d-5p
;
hsa-mir-302b-5p
;
hsa-mir-5583-5p
;
hsa-mir-3129-3p
;
hsa-mir-5010-3p
;
hsa-mir-2113
;
hsa-mir-147a
;
hsa-mir-6818-5p
;
hsa-mir-580-3p
;
hsa-mir-4461
;
hsa-mir-519e-3p
;
hsa-mir-515-3p
;
hsa-mir-33b-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-3680-3p
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-450b-5p
;
hsa-mir-4325
;
hsa-mir-7703
;
hsa-mir-5582-3p
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-129-5p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-93-5p
;
hsa-mir-17-5p
;
hsa-mir-107
Nearest miRNA
hsa-mir-12113/Upstream/2787288; hsa-mir-1243/Downstream/5422584;
Nearest TSS
ENST00000502981/Upstream/20975;
ENST00000609234/Downstream/9992;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/103699
,
chr4-CpG: 144/Downstream/45791
Upstream sequence
gagttctctttcccaattcctctggccagagagacggctttcttcttgggattttaagtacatataccactatggcaatgtaattttacaaatggagatg
Downstream sequence
gtctcagggcacagctgggagagaaaaaaaggggggaattttctttgtcctatgactagaaataaagggtttctcttggagtttttgctaactgctgcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL182
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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