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TVIS44014673
Basic Information
VIS ID
TVIS44014673
Fusion event
HTLV-1-HSPA4L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.1
Reference genome
GRCh37/hg19
Start
128749488/127828333 (Hg38)
End
128749488/127828333 (Hg38)
Orient
+
Location type
Intronic
Target gene
HSPA4L
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-16-5p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-3646
;
hsa-mir-3688-3p
;
hsa-mir-3908
;
hsa-mir-5093
;
hsa-mir-6792-5p
;
hsa-mir-6838-5p
;
hsa-mir-448
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-937-5p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-5702
;
hsa-mir-6889-3p
;
hsa-mir-6849-3p
;
hsa-mir-3934-5p
;
hsa-mir-1208
;
hsa-mir-6760-3p
;
hsa-mir-6504-3p
;
hsa-mir-552-3p
;
hsa-mir-5698
;
hsa-mir-744-3p
;
hsa-mir-4423-5p
;
hsa-mir-6501-5p
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6499-3p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-3664-5p
;
hsa-mir-5089-5p
;
hsa-mir-6508-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-6506-5p
;
hsa-mir-6853-5p
;
hsa-mir-619-5p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-4438
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-361-5p
;
hsa-mir-889-3p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-2115-3p
;
hsa-mir-3074-3p
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-196b-5p
;
hsa-mir-196a-5p
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-1183
;
hsa-mir-6878-3p
;
hsa-mir-7641
;
hsa-mir-378a-5p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-4695-3p
;
hsa-mir-4707-3p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-18a-3p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-212-5p
;
hsa-mir-6894-3p
;
hsa-mir-203b-3p
;
hsa-mir-7158-3p
;
hsa-mir-5001-3p
;
hsa-mir-4312
;
hsa-mir-4763-5p
;
hsa-mir-6778-3p
;
hsa-mir-4680-5p
;
hsa-mir-150-5p
;
hsa-mir-186-3p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-9-3p
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-3529-3p
;
hsa-mir-4429
;
hsa-mir-320d
;
hsa-mir-320c
;
hsa-mir-320b
;
hsa-mir-320a
;
hsa-mir-1289
;
hsa-mir-215-3p
;
hsa-mir-3194-3p
;
hsa-mir-3198
;
hsa-mir-4294
;
hsa-mir-4309
;
hsa-mir-431-5p
;
hsa-mir-4534
;
hsa-mir-500b-3p
;
hsa-mir-5691
;
hsa-mir-5693
;
hsa-mir-6514-5p
;
hsa-mir-6773-3p
;
hsa-mir-6805-3p
;
hsa-mir-6879-3p
;
hsa-mir-8082
;
hsa-mir-924
Nearest miRNA
hsa-mir-12113/Upstream/2321026; hsa-mir-1305/Downstream/15515127;
Nearest TSS
ENST00000502981/Upstream/15315;
ENST00000503914/Downstream/15707;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/45273
,
chr4-CpG: 74/Downstream/52398
Upstream sequence
ACTCTAAGTAAATATTCTCTGTAATCCCTAGTTTTTGTCATTGATGTTAAACATGCATTAGTAGGAAGAAGAGACCAGCACCAGAAATATTCAAGCATGT
Downstream sequence
CAAaatagcttacatttattgtgcacatcatgaattttaagtactttatgtggattatctcaccaggatatatcctatacaaagttaatgctattatctt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL182
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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