Basic Information
VIS ID
TVIS44014687
Fusion event
HTLV-1-C5orf38 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
2758118/2758004 (Hg38)
End
2758118/2758004 (Hg38)
Orient
+
Location type
Intronic
Target gene
C5orf38
miRNAs that regulate target gene
hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-6851-5p ; hsa-mir-7106-5p ; hsa-mir-3689d ; hsa-mir-765 ; hsa-mir-6134 ; hsa-mir-1292-3p ; hsa-mir-6746-3p
Nearest miRNA
hsa-mir-4277/Upstream/1049136; hsa-mir-10397/Downstream/4069849;
Nearest TSS
ENST00000502646/Upstream/5739; ENST00000515086/Downstream/77135;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1094, chr5-CpG: 23/Downstream/108581
Nearby gene
C5orf38(No orient, 2607)
Upstream sequence
GCCGCATCTGAAAGCGCAGAAGGTGCGTGCTCCCTGGCACCCAGCACACAGGTGTTGGGGAAGCGGGGACGAGGCAGCCCtggagcatggtttgcaggag
Downstream sequence
tgcaagactgcaagcctcctccacggccaccactccaggcctggataaagaattcgtggcatatttcagggaacagaatgtcccctggggcgaaagggga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate