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TVIS44014705
Basic Information
VIS ID
TVIS44014705
Fusion event
HTLV-1-ATXN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
16523911/16523680 (Hg38)
End
16523911/16523680 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATXN1
miRNAs that regulate target gene
hsa-mir-101-3p
;
hsa-mir-19b-3p
;
hsa-mir-19a-3p
;
hsa-mir-130a-3p
;
hsa-mir-125b-5p
;
hsa-mir-590-3p
;
hsa-mir-335-5p
;
hsa-mir-340-5p
;
hsa-mir-186-5p
;
hsa-mir-125a-5p
;
hsa-mir-221-3p
;
hsa-mir-96-5p
;
hsa-mir-93-5p
;
hsa-mir-32-5p
;
hsa-mir-877-3p
;
hsa-mir-320a
;
hsa-mir-92a-3p
;
hsa-mir-374a-5p
;
hsa-mir-374b-5p
;
hsa-mir-627-3p
;
hsa-mir-1228-3p
;
hsa-mir-140-3p
;
hsa-mir-204-5p
;
hsa-mir-211-5p
;
hsa-mir-657
;
hsa-mir-4302
;
hsa-mir-6733-3p
;
hsa-mir-4503
;
hsa-mir-6792-5p
;
hsa-mir-4736
;
hsa-mir-6740-5p
;
hsa-mir-6808-3p
;
hsa-mir-1277-5p
;
hsa-mir-4768-5p
;
hsa-mir-6515-3p
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4796-3p
;
hsa-mir-4795-3p
;
hsa-mir-515-5p
;
hsa-mir-519e-5p
;
hsa-mir-20a-5p
;
hsa-mir-218-5p
;
hsa-mir-106b-5p
;
hsa-mir-433-3p
;
hsa-mir-1206
;
hsa-mir-7154-5p
;
hsa-mir-549a
;
hsa-mir-494-3p
;
hsa-mir-8060
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-5692a
;
hsa-mir-8056
;
hsa-mir-1290
;
hsa-mir-876-5p
;
hsa-mir-3167
;
hsa-mir-6849-5p
;
hsa-mir-3681-5p
;
hsa-mir-548g-3p
;
hsa-mir-16-1-3p
;
hsa-mir-144-3p
;
hsa-mir-595
;
hsa-mir-548ah-5p
;
hsa-mir-5590-3p
;
hsa-mir-3609
;
hsa-mir-142-5p
;
hsa-mir-17-5p
;
hsa-mir-20b-5p
;
hsa-mir-106a-5p
;
hsa-mir-519d-3p
;
hsa-mir-526b-3p
;
hsa-mir-4446-5p
;
hsa-mir-5006-3p
;
hsa-mir-4755-5p
;
hsa-mir-4309
;
hsa-mir-3198
;
hsa-mir-6883-3p
;
hsa-mir-4653-3p
;
hsa-mir-1203
;
hsa-mir-454-5p
;
hsa-mir-6736-3p
;
hsa-mir-382-5p
;
hsa-mir-5010-3p
;
hsa-mir-2113
;
hsa-mir-758-3p
;
hsa-mir-4536-5p
;
hsa-mir-542-3p
;
hsa-mir-4504
;
hsa-mir-3119
;
hsa-mir-576-3p
;
hsa-mir-6885-3p
;
hsa-mir-491-3p
;
hsa-mir-4423-3p
;
hsa-mir-361-3p
;
hsa-mir-4729
;
hsa-mir-1910-5p
;
hsa-mir-455-3p
;
hsa-mir-449c-5p
;
hsa-mir-34b-5p
;
hsa-mir-2682-5p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-6077
;
hsa-mir-146b-3p
;
hsa-mir-6799-3p
;
hsa-mir-3173-5p
;
hsa-mir-7976
;
hsa-mir-4468
;
hsa-mir-4699-5p
;
hsa-mir-3688-3p
;
hsa-mir-8076
;
hsa-mir-371b-3p
;
hsa-mir-302f
;
hsa-mir-874-3p
;
hsa-mir-7-5p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-1247-5p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-4753-3p
;
hsa-mir-6873-3p
;
hsa-mir-630
;
hsa-mir-942-5p
;
hsa-mir-1236-3p
;
hsa-mir-136-5p
;
hsa-mir-6832-3p
;
hsa-mir-6866-3p
;
hsa-mir-188-5p
;
hsa-mir-92b-3p
Nearest miRNA
hsa-mir-3691/Upstream/382056; hsa-mir-10398/Downstream/2048104;
Nearest TSS
ENST00000381078/Upstream/195399;
ENST00000450930/Downstream/226412;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/195348
,
chr6-CpG: 238/Downstream/236267
Upstream sequence
AATAAATAACCAAAGTACCCCATTCCTGCACTTTGCTCTTTCCCAAAATGGTATACCCACAGCTTCACTCCCTGCAGTGATCTGTATGTAATTAGGCTCA
Downstream sequence
TATGGGAATGTGGACTTGGCAGAGGGGCGCTGGAGGCCACATATCAGGCTGACTGAGTAATCCCGTGAGGAAGCCACAGTGTCTGAGATACTGACGGGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL182
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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