Basic Information
VIS ID
TVIS44014711
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
128270499/127949354 (Hg38)
End
128270499/127949354 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/1464641; hsa-mir-1202/Downstream/3842818;
Nearest TSS
ENST00000381078/Upstream/30723; ENST00000417390/Downstream/58723;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/432793, chr6-CpG: 173/Downstream/569659
Nearby gene
PTPRK(-19425) ;
Nearest cancer related gene
PTPRK(TSG, -19425) ;
Upstream sequence
tggaatgaaaaaaaaaattgtaagattgcagacaaggagatttggggaagatatatgtgggtagaattatcagagaaagcatattgcatattaaaactag
Downstream sequence
agaatatccaccgaaaccgagtggacagaattatacagctaatcgatgtttacacagcttctgttcttagccactgccaaatggctggggtgacagccac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate