Basic Information
VIS ID
TVIS44014726
Fusion event
HTLV-1-LOC105375630 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
89763791/88751562 (Hg38)
End
89763791/88751562 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375630
Nearest miRNA
hsa-mir-12123/Upstream/8510089; hsa-mir-10400/Downstream/2453923;
Nearest TSS
ENST00000518652/Upstream/51271; ENST00000517696/Downstream/57346;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/423310, chr8-CpG: 92/Downstream/1005745
Nearby gene
MMP16(-424074) ;
Upstream sequence
GGAGAAATGTACAAAATCATTCTTTGTAGAAAGCTCATTGTACATAAACCAAGAATATTCCTTTTTGATGGGTTTTCATAAAACCTTCTGCATAAAATGC
Downstream sequence
TTTCTTACTTCTTACTGATAGCATTCACTGAGATAAGATATtgacacaggatattttcactgctgcttcaccagccagagacctccgtggccagcagcac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate