Basic Information
VIS ID
TVIS44014773
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
34598373/34580256 (Hg38)
End
34598373/34580256 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-23c/Upstream/1938697; hsa-let-7f-2/Downstream/3443639;
Nearest TSS
ENST00000429181/Upstream/164719; ENST00000329357/Downstream/77032;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/192085, chrX-CpG: 131/Downstream/76134
Nearby gene
TMEM47(-46808) ;
Upstream sequence
TCTGAATGTCTTTTTTTCCTTACAACATGTATTCTGATATCAGTACTTCCATTTGTACAGTCAACAGAAACTAAGAAATTAGCTGCATGTGTCTCTCTTA
Downstream sequence
AGAACTCCTTCTGAAACTCCTTACTTGAGCTCTCACATTTGTTTGACTTCTTATGACTGCAGCACCTTAGCAAATATATTCTAAGGATATCATCGAGCTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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