Basic Information
VIS ID
TVIS44014795
Fusion event
HTLV-1-CNTN5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
100016962/100146230 (Hg38)
End
100016962/100146230 (Hg38)
Orient
+
Location type
Intronic
Target gene
CNTN5
Nearest miRNA
hsa-mir-10392/Upstream/3804704; hsa-let-7a-2/Downstream/1373590;
Nearest TSS
ENST00000527297/Upstream/75829; ENST00000524560/Downstream/44947;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1125139, chr11-CpG: 64/Downstream/540962
Upstream sequence
ATTTTGTGTTTTATGTGAGGGAAATAACAATCAGTAATACTTAGGGTTTTGAATTCAGGGTTTGATTAAGGGTGACTGTATTACAATTTTTCTCATCTAA
Downstream sequence
ATAGTGTTCATTaaatattagaagaaaagagctcaaaatgtaggcagtgattatgtctaaatgttggaatcatacaagatctttactttcttccgtacac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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