Basic Information
VIS ID
TVIS44014827
Fusion event
HTLV-1-LINC01973 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
75877227/77881145 (Hg38)
End
75877227/77881145 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
LINC01973
Nearest miRNA
hsa-mir-10226/Upstream/484091; hsa-mir-1250/Downstream/1826031;
Nearest TSS
ENST00000595228/Upstream/152586; ENST00000588549/Downstream/2942;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/87674, chr17-CpG: 36/Downstream/6576
Upstream sequence
ggagaaggctggtGTCCCGAGCTCAGCATCATTATTCAGCCAGACCCTCCCCAGCATAGTAGCGCCCACCCCGCTGGCAGGATAGGAGGATGGAGGATGG
Downstream sequence
GTACTTCCCCCCTCCCCTTCCACCTGGGGCAGGGAGAATCTGCCAGGAGTGCCCCGTCCCTGAGCTCCAGCCTCCCCCACCACCCCCAGTGACAAAGACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate