Basic Information
VIS ID
TVIS44014847
Fusion event
HTLV-1-PPP4R1L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
End
56842978/58267922 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/946331; hsa-mir-1-1/Downstream/549693;
Upstream sequence
CTCCACAGCCCCATAGCATGCAACAGGCAGCCTCATGAAACCAGACATCCAGCCTCCTGCCTTCTCCAGCTGCTACTCAGCACCCACAACCACACCTCTC
Downstream sequence
TGCTTAACTAGCAACTCACCCATACTTCACAGTGGGGGTGAACAAGAGGAAAGGAGATAAGCCAAGCTAGCCTGGAGCACAGCCCTGGAGCACAGCGACA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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