Basic Information
VIS ID
TVIS44014852
Fusion event
HTLV-1-ZNF660-ZNF197 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
44653979/44612487 (Hg38)
End
44653979/44612487 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF660-ZNF197
Nearest miRNA
hsa-mir-12127/Upstream/498177; hsa-let-7g/Downstream/249401;
Nearest TSS
ENST00000440867/Upstream/27523; ENST00000344387/Downstream/12310;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/27185, chr3-CpG: 38/Downstream/12498
Nearby gene
ZNF197-AS1(No orient, 4641)
Upstream sequence
ggacacaataataaaagaatactacaggccagtatccctgatgaacataggggcaatagtcttcaacaaaatactagcaaataaaatctaaccaaaagat
Downstream sequence
aatataccatgatcaagtgggatttaacccagggatgaaaggatgtttcaaaatacgcaaatcaataaatgtgatacatcacataaacagaatgaagaac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate