Basic Information
VIS ID
TVIS44014867
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
31700028/31698406 (Hg38)
End
31700028/31698406 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/2878738; hsa-mir-1243/Downstream/4727960;
Nearest TSS
ENST00000502981/Upstream/191740; ENST00000513211/Downstream/298991;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/975186, chr4-CpG: 100/Downstream/4545603
Nearby gene
LOC105374566(+3654) ;
Upstream sequence
tctctttcttAACCCTGTCACATTCTTCTCAAGGACTGAAGCGGTAGCAAGTGAATGTTCTATCTTGGTTTAACTAGTCCCTAAGGGGTACTTCAGAGGT
Downstream sequence
AGAAAAAAGAAGCTTAAGATTCAGTGAAGGACAAAGGGAAAAAGGAATACAGGTGGTGAAAATCAGCTTATGATCCCTGGTCCCTTGTGATACATTATAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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