Basic Information
VIS ID
TVIS44014873
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69611097/68745379 (Hg38)
End
69611097/68745379 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2468451; hsa-mir-1243/Downstream/7828189;
Nearest TSS
ENST00000502981/Upstream/74751; ENST00000458688/Downstream/70614;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/395176, chr4-CpG: 55/Downstream/1942758
Nearby gene
UGT2B10(+70614) ;
Upstream sequence
tactttgtaaatcattaatatcaaaagtaacattggatgtgaaagctccctgtaaatgggcctttacaaggctccaggaatattcactttggttatattc
Downstream sequence
caaattggtcacacaaatatgagtatgattaaaatgacaatgcaattgctgatgcaactgcaaactttgttatttgttctcctagccaaagaacagtagc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate