Basic Information
VIS ID
TVIS44014927
Fusion event
HTLV-1-LOC102724057 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
88402037/85787122 (Hg38)
End
88402037/85787122 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102724057
Nearest miRNA
hsa-mir-101-2/Upstream/1817265; hsa-let-7a-1/Downstream/2958714;
Nearest TSS
ENST00000422679/Upstream/593; ENST00000416045/Downstream/4412;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/44672, chr9-CpG: 127/Downstream/17949
Nearby gene
LOC389765(+18880) ;
Upstream sequence
TGTCAGAGGGAGTCACCTGCTGCATATGTGGGCTAAGACAACCTCTCAGCTTTATGGATTGAGGCTCATTTACAGTCCTCAGAGCTCACAGAAATGGTCA
Downstream sequence
GTCTTGACTTTTTAAACATGCTCACTGTTCTGTTTCTGGAAATTTTTTGGATTTTTAAAAATTTATAATGCTATCTTTTTTGTTTGCTAATATTATGCAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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