Basic Information
VIS ID
TVIS44014940
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q25
Reference genome
GRCh37/hg19
Start
125223033/126089050 (Hg38)
End
125223033/126089050 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/4717997; hsa-mir-105-1/Downstream/8080328;
Nearest TSS
ENST00000429181/Upstream/768930; ENST00000438994/Downstream/20712;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/768749, chrX-CpG: 104/Downstream/76212
Nearby gene
LOC101928495(No orient, 20712)
Upstream sequence
cttgcacatgcaccccgtaatataaaattaaagttaaagaaaaaaaAAACACAAAATGCCCTTCTGATTATATATTTTTCTTGTACCCCAAATTTGATTA
Downstream sequence
AATGACTTAATAAGAAAAATTGGAATTATTTCTATAAGTCTTTTTCCCCCCTAACATCCAGCCTATGCTGATTTATTATTCTAATGATTGAAGATTCTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate