VISDB Viral Integration Site DataBase

VIS ID

TVIS44014965

Fusion event

HTLV-1-TIMM10 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q12.1

Reference genome

Start

End

57302530/57535057 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-mir-125b-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-4642 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-4279 ; hsa-mir-653-3p ; hsa-mir-6815-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-6845-3p ; hsa-mir-1304-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-892b ; hsa-mir-668-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-5587-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6801-5p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-4716-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4781-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4668-3p ; hsa-mir-377-3p ; hsa-mir-1236-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6849-3p ; hsa-mir-1228-3p ; hsa-mir-6800-3p ; hsa-mir-7109-3p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-548e-5p ; hsa-mir-6778-3p ; hsa-mir-512-3p

Nearest miRNA

hsa-mir-129-2/Upstream/791076; hsa-let-7a-2/Downstream/106141;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/19225, chr11-CpG: 62/Downstream/32518

Nearby gene

TIMM10(-4298) ;

Upstream sequence

agtgctttatacaccgcgcccggccaacaaatttttaagtgcacaaaatagtattgttaactatatgtaccatattgtacacagatttctagaacttatt

Downstream sequence

catcttgcataactgaaattgtatacccattgaacagcaactctccatctccccagctgctcagcctctggaaaaccattGCTCTTATTGATGATGATGC