Basic Information
VIS ID
TVIS44014975
Fusion event
HTLV-1-GALNT14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
31175336/30952470 (Hg38)
End
31175336/30952470 (Hg38)
Orient
-
Location type
Intronic
Target gene
GALNT14
miRNAs that regulate target gene
hsa-mir-125a-5p
Nearest miRNA
hsa-mir-1301/Upstream/2956021; hsa-mir-10b/Downstream/1579683;
Nearest TSS
ENST00000437798/Upstream/27647; ENST00000449780/Downstream/3214;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/504616, chr2-CpG: 146/Downstream/184985
Upstream sequence
caatgatagactggattaagaaaatgtggcacatatacaccatggaatactatgcagccataaaaaatgatgagttcatgtcctttgtagggacatggat
Downstream sequence
gaaattggaaatcatcattctcagtaaactattgcaagaacaaaaaaccaaacaccgcatattctcactcataagtgggaattgaacaatgagatcacat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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