Basic Information
VIS ID
TVIS44015043
Fusion event
HTLV-1-LOC105375523 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
136026035/136341287 (Hg38)
End
136026035/136341287 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375523
Nearest miRNA
hsa-mir-10525/Upstream/1134209; hsa-mir-10399/Downstream/561880;
Nearest TSS
ENST00000635602/Upstream/248330; ENST00000437569/Downstream/63976;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/363763, chr7-CpG: 154/Downstream/527820
Nearby gene
MTPN(-363831) ;
Upstream sequence
ATGTTTAGAGTTGTCTGACAACTCCCTAGGAAACTTTTAACAACCATTAATTTAGAAACAATTTTGCTTCTGTAATTCATTtctcaattggttgtgatgg
Downstream sequence
aagtaattgtcatatccagagggagaatcttgacttcaggcaatacataaatatctacactcttcagaaacagcattgttttagtggtaaatgccctcag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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