Basic Information
VIS ID
TVIS44015065
Fusion event
HTLV-1-LINC02408 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
67935442/67541662 (Hg38)
End
67935442/67541662 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC02408
Nearest miRNA
hsa-let-7i/Upstream/1290505; hsa-mir-1178/Downstream/1731495;
Nearest TSS
ENST00000382841/Upstream/21580; ENST00000537632/Downstream/45644;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/271395, chr12-CpG: 181/Downstream/106724
Upstream sequence
GAAGACAGGGCAAAATTCAAGAACCTACATAATTTAACCATCGCAAATATTCAACCTAAACCTCCCTCTAAACACTGAACTCTTCACTCACTCCCATTTA
Downstream sequence
TACCTTCCATATCGTATTAATGCTCCCCTTTCTCCCGGATGCTTATGAGTATTTCAGATAAGTGTAACTGATCACCTAATCTTTCTGCTTCCTCCTCCCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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