Basic Information
VIS ID
TVIS44015069
Fusion event
HTLV-1-LINC00457 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
35029479/34455342 (Hg38)
End
35029479/34455342 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA13A
Target gene
LINC00457
Nearest miRNA
hsa-mir-2276/Upstream/10292838; hsa-mir-1267/Downstream/5208692;
Nearest TSS
ENST00000623511/Upstream/107299; ENST00000497540/Downstream/79008;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/636986, chr13-CpG: 79/Downstream/486892
Upstream sequence
caaagtcctgggattacaggcatgagccaccgcgcccagccCTCCAAAAACTTTTAAAGTATCAGCTAGATCACATCAAAGTTCAaactttctgaaataa
Downstream sequence
gctaacagccccctaaaaaccgtctgggatgccttgggagataatTGGAGAATTGAAAGACATTTGTTAAGTTTTTGCAAACCTTTGGAATTCTCAAATA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate