Basic Information
VIS ID
TVIS44015070
Fusion event
HTLV-1-LOC105370198 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
48742366/48168230 (Hg38)
End
48742366/48168230 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370198
Nearest miRNA
hsa-mir-2276/Upstream/3972030; hsa-mir-1267/Downstream/1828185;
Nearest TSS
ENST00000623511/Upstream/73099; ENST00000607866/Downstream/64928;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/72974, chr13-CpG: 84/Downstream/64616
Nearby gene
ITM2B(+64908) ;
Upstream sequence
agacggattagagtttaaagctgctcaagtggctgcgacttgatggtaaaatctcaaggaggagagagttgcagagaaataaacccaaaaggctacatgc
Downstream sequence
aatctccccttgagatgtctgcaaactcctaagctgagcaagcacaagcagagactgcaggagaaccaaaagaaaagcagcagctaggaggctggagagc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate