Basic Information
VIS ID
TVIS44015101
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
33471385/32099072 (Hg38)
End
33471385/32099072 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1723694; hsa-mir-3197/Downstream/1451590;
Nearest TSS
ENST00000624081/Upstream/12777; ENST00000453549/Downstream/98741;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/224776, chr21-CpG: 63/Downstream/179525
Nearby gene
LINC00159(-12777) ;
Upstream sequence
AGAATAGCCTGCAATGCTGTGAAGTTCCCTCCCAGGGAGAAAGAGGTCATCTTGAGAACTTATATCCCACAGCCCCCAGTCTCCCATGCTGGGACCTTCT
Downstream sequence
CACCTCTTCTGTCCTGGCAAGCAGCCAAGTGTGGCTCAGAGGCTGAGCAGAGGGAAAGATGTTGGCCCTTTGCTCCTCAGCATCAGTGGGCTTAAGTGCG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate