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TVIS44015102
Basic Information
VIS ID
TVIS44015102
Fusion event
HTLV-1-BACE2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
42577693/41205766 (Hg38)
End
42577693/41205766 (Hg38)
Orient
-
Location type
Intronic
Target gene
BACE2
miRNAs that regulate target gene
hsa-mir-484
;
hsa-mir-2054
;
hsa-mir-1299
;
hsa-mir-3686
;
hsa-mir-4662a-5p
;
hsa-mir-5189-3p
;
hsa-mir-3607-3p
;
hsa-mir-4778-5p
;
hsa-mir-3651
;
hsa-mir-1277-5p
;
hsa-mir-302c-5p
;
hsa-mir-6739-5p
;
hsa-mir-3153
;
hsa-mir-6733-5p
;
hsa-mir-211-3p
;
hsa-mir-7845-5p
;
hsa-mir-5584-5p
;
hsa-mir-6859-5p
;
hsa-mir-3916
;
hsa-mir-3125
;
hsa-mir-583
;
hsa-mir-6868-3p
;
hsa-mir-670-5p
;
hsa-mir-2277-3p
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-4319
;
hsa-mir-125b-5p
;
hsa-mir-125a-5p
;
hsa-mir-4732-3p
;
hsa-mir-345-3p
;
hsa-mir-1207-3p
;
hsa-mir-141-5p
;
hsa-mir-4526
;
hsa-mir-3660
;
hsa-mir-498
;
hsa-mir-4279
;
hsa-mir-525-5p
;
hsa-mir-520a-5p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-1303
;
hsa-mir-5096
;
hsa-mir-3149
;
hsa-mir-3912-5p
;
hsa-mir-197-3p
;
hsa-mir-411-5p
;
hsa-mir-6755-3p
;
hsa-mir-198
;
hsa-mir-6832-5p
;
hsa-mir-193b-5p
;
hsa-mir-4716-5p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-483-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-378a-5p
;
hsa-mir-6131
;
hsa-mir-3663-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-874-3p
;
hsa-mir-3157-3p
;
hsa-mir-4448
;
hsa-mir-6861-3p
;
hsa-mir-6821-3p
;
hsa-mir-3182
;
hsa-mir-149-5p
;
hsa-mir-4794
;
hsa-mir-664a-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-1248
;
hsa-mir-1237-3p
;
hsa-mir-4723-3p
;
hsa-mir-6769b-3p
;
hsa-mir-3183
;
hsa-mir-6800-3p
;
hsa-mir-3064-5p
;
hsa-mir-6504-5p
;
hsa-mir-1226-5p
;
hsa-mir-25-5p
;
hsa-mir-3616-3p
;
hsa-mir-433-5p
;
hsa-mir-4487
;
hsa-mir-4710
;
hsa-mir-4721
;
hsa-mir-4730
;
hsa-mir-553
;
hsa-mir-7160-3p
Nearest miRNA
hsa-let-7c/Upstream/38137; hsa-mir-5692b/Downstream/541006;
Nearest TSS
ENST00000624081/Upstream/18978;
ENST00000470864/Downstream/19710;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/36821
,
chr21-CpG: 16/Downstream/40124
Upstream sequence
GTTGGGTGGCCGAGGAGAAATGAAATTTTGAGTGGAAAACCTCACATGAATTGTCTGTAGTTGCTTGTACTTCATCCCTCACCAGTGCAAAAGCCAATTC
Downstream sequence
CACAGGAATTGAAAACTGTTATGAAAGAGAAGCCTGGTCTTCCGTCTTAACATCGGGTCATGAATTCAATGGGGAACactgtatcttcttcatctctatg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL128
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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