Basic Information
VIS ID
TVIS44015117
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
64434397/65138570 (Hg38)
End
64434397/65138570 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/5434867; hsa-mir-103a-1/Downstream/7030897;
Nearest TSS
ENST00000502646/Upstream/117956; ENST00000508982/Downstream/60195;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/35181, chr5-CpG: 43/Downstream/424378
Nearby gene
ADAMTS6(-10166) ;
Upstream sequence
AGTTCTTGCCCAAAGCAAAGAACACCAAATTAAATATTTTCAGTGGTGTAGGAAATACCATTTGTTAGCATCCCATTCCCTCATAAGGATATTGCCTTAG
Downstream sequence
CTAAATACATAACCTCTCACTCTTTCCTGCATTAGAACTACTTGAAGGGACCCCATCTGTCTGTCTCATAGGGCTTTTCTCTTAATCAGTTATTGGCAAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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