Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene500889205020271350351910501907685020101350201533502032515020376750205319501887675018980150198140501990595020036250200421502009945020105350220415
Basic Information
VIS ID
TVIS44015132
Fusion event
HTLV-1-CCNB3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
115148001/50220415 (Hg38)
End
115148001/50220415 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCNB3
Nearest miRNA
hsa-mir-1587/Upstream/205732; hsa-let-7f-2/Downstream/2116142;
Nearest TSS
ENST00000429181/Upstream/15470; ENST00000487204/Downstream/64121;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/297031, chrX-CpG: 16/Downstream/60921
Nearby gene
DANT2(No orient, 62557)
Upstream sequence
tggtgagagagggcatccctgtcttgtgccagttttcaaaaggaatgcttccagtttttgcccattcagtatgatattggctgtgggtttgtcataaata
Downstream sequence
gctcttaatattttgagatacatcccatcaatacctagtttatttagtatttttagcatgaagtgctattgaattttgttgaaggccttttctgcatcta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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