Basic Information
VIS ID
TVIS44015135
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
25194342/24867851 (Hg38)
End
25194342/24867851 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/938704; hsa-mir-101-1/Downstream/51494;
Nearest TSS
ENST00000473358/Upstream/122442; ENST00000456316/Downstream/60947;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/18975, chr1-CpG: 47/Downstream/34154
Nearby gene
CLIC4(+23527) ;
Upstream sequence
CGCACGCCCAGAGAGGGGCTGAGATCATACCACCAGGGACCTGGTGTTGGTTCCACAAGAGGCTCAGGGACACACTTCCAGAATTTTGAGAGCACCCCTA
Downstream sequence
GCAGAGGCAGGGACTTGGACTGGTTGACCTGGCTTTCCCACACCCTCAAAACCTCAAAATGTCCAATGTCCATCCACTGATCATGATGGGTCTTTCTAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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