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VISDB
Viral Integration Site DataBase
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TVIS44015168
Basic Information
VIS ID
TVIS44015168
Fusion event
HTLV-1-SHISA6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
11151312/11247995 (Hg38)
End
11151312/11247995 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
SHISA6
miRNAs that regulate target gene
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-5196-5p
;
hsa-mir-6797-5p
;
hsa-mir-4747-5p
;
hsa-mir-1249-5p
;
hsa-mir-4683
;
hsa-mir-4722-5p
;
hsa-mir-1286
;
hsa-mir-873-5p
;
hsa-mir-4708-5p
;
hsa-mir-9500
;
hsa-mir-4459
;
hsa-mir-4779
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-491-5p
;
hsa-mir-7847-3p
;
hsa-mir-92a-2-5p
;
hsa-mir-6825-5p
;
hsa-mir-939-5p
;
hsa-mir-1343-5p
;
hsa-mir-3175
;
hsa-mir-7106-5p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-766-5p
;
hsa-mir-3665
;
hsa-mir-6134
;
hsa-mir-3928-3p
;
hsa-mir-6777-5p
;
hsa-mir-6889-5p
;
hsa-mir-194-3p
;
hsa-mir-5693
;
hsa-mir-2278
;
hsa-mir-6875-3p
;
hsa-mir-6502-5p
;
hsa-mir-1301-5p
;
hsa-mir-4778-3p
;
hsa-mir-26a-2-3p
;
hsa-mir-26a-1-3p
;
hsa-mir-6731-3p
;
hsa-mir-499b-5p
;
hsa-mir-4494
;
hsa-mir-506-5p
;
hsa-mir-892c-5p
;
hsa-mir-3680-5p
;
hsa-mir-6741-3p
;
hsa-mir-6867-3p
;
hsa-mir-6749-3p
;
hsa-mir-6826-3p
;
hsa-mir-1298-5p
;
hsa-mir-7110-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-205-5p
;
hsa-mir-6769b-3p
;
hsa-mir-4723-3p
;
hsa-mir-3183
;
hsa-mir-5193
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-6795-3p
;
hsa-mir-6887-3p
;
hsa-mir-502-5p
;
hsa-mir-1915-5p
;
hsa-mir-6841-3p
Nearest miRNA
hsa-mir-1253/Upstream/3060991; hsa-mir-10226/Downstream/833904;
Nearest TSS
ENST00000595228/Upstream/6054;
ENST00000577346/Downstream/40210;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/5896
,
chr17-CpG: 32/Downstream/309759
Upstream sequence
tcccaagtagctaggactacaggcgcccgccaccacacctggctaattttttgtatttttagtagagacagcgtttcaccatgttagccagaatggtctc
Downstream sequence
gatctcctgacctcatgctctgcccacctctgcctcccaaagtgctgggattacaggtgtgagacacggagcctggccTCTAGTGTCTTTCTTTGCAGAT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL242
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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