Basic Information
VIS ID
TVIS44015197
Fusion event
HTLV-1-LOC105369842 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
75290157/74896377 (Hg38)
End
75290157/74896377 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369842
Nearest miRNA
hsa-let-7i/Upstream/5311554; hsa-mir-1178/Downstream/4522880;
Nearest TSS
ENST00000382841/Upstream/357744; ENST00000549762/Downstream/124592;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/358278, chr12-CpG: 68/Downstream/310924
Nearby gene
KCNC2(-143701) ;
Upstream sequence
atataaaagatttttataaatggaacacctttttagagcactgaccatgaatggagcttacaggactggaggctgctgtgggtgagtcagtgagcagtgg
Downstream sequence
tgagtgaatgtgaaggactgggaaattcctgaacactattgtagactttatacgcactctacacttaagctacactgaagttatttaaacaatactctct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate