Basic Information
VIS ID
TVIS44015233
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
2281261/2281261 (Hg38)
End
2281261/2281261 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1302-9/Upstream/2250980; hsa-let-7a-1/Downstream/2569036;
Nearest TSS
ENST00000422679/Upstream/99690; ENST00000445631/Downstream/240758;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/39159, chr9-CpG: 219/Downstream/340047
Nearby gene
SMARCA2(+87638) ;
Nearest cancer related gene
SMARCA2(TSG, +87638) ;
Upstream sequence
ataaaacaagtgaaaatggccagtccctgacttaactgatgactttgcaccacaaaagaagtgacaatggccggtcgctgccttaaccgatgacattatc
Downstream sequence
ttgtgaaattccttctcctggctcatcctggctaaaaagcttcctcactgagcaccttgtgaccccccatccctgcccgccagagaacaacccccctttg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate