Basic Information
VIS ID
TVIS44015239
Fusion event
HTLV-1-IMMP1L integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
31526256/31504709 (Hg38)
End
31526256/31504709 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
IMMP1L
Nearest miRNA
hsa-mir-210/Upstream/3027161; hsa-let-7a-2/Downstream/3437128;
Nearest TSS
ENST00000527297/Upstream/48371; ENST00000638764/Downstream/4854;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/134758, chr11-CpG: 33/Downstream/4875
Upstream sequence
attgaagaaatggccacaaatgggaaactatccaaatcccttctaacagtagaacacataataaattataatacatttatataatactatacagcaataa
Downstream sequence
gaatagatcagccacaacgacacacattaacaaggatcatttcacaaaaataatgttaagcaaaagaagtcaaacatggaatctaatagtggatctaatg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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