Basic Information
VIS ID
TVIS44015301
Fusion event
HTLV-1-CFAP97 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
186111951/185190797 (Hg38)
End
186111951/185190797 (Hg38)
Orient
-
Location type
Exonic
Target gene
CFAP97
miRNAs that regulate target gene
hsa-mir-218-5p
Nearest miRNA
hsa-mir-12113/Upstream/252357;
Nearest TSS
ENST00000502981/Upstream/8278; ENST00000506896/Downstream/13168;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/46949, chr4-CpG: 110/Downstream/12714
Upstream sequence
AATACTTTTTCCTTATGCTTTTTTTAACGTTAGTAGATGGTTTAGCGGACTTGGACTTCACATGGTATTTCTTCCCATCATCACTGCTTTCCTCTCCATC
Downstream sequence
TGTGTAGTAATCATCTTCACCTTCTTTTACAATTTTGGGAATTCTATTTGGAATGGACACGTGTATTTTAAGTCCTGTTGTAACATCACACAATTTTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate