Basic Information
VIS ID
TVIS44015305
Fusion event
HTLV-1-ITGA9-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
37879411/37837920 (Hg38)
End
37879411/37837920 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ITGA9-AS1
Nearest miRNA
hsa-mir-12127/Upstream/2093361; hsa-let-7g/Downstream/131484;
Nearest TSS
ENST00000440867/Upstream/57905; ENST00000435525/Downstream/24040;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/384873, chr3-CpG: 203/Downstream/22527
Upstream sequence
caggaacaactgatctatgtgtttgtaattttgacaaatattgccaaattgttctctataagggctgtaccaagtcactcccacccacagtgtgtgGTTC
Downstream sequence
CATTTGATGTATTTTCAATGGTTTTCTGAAGACAGAACATGTTCTGATCATTTCTTGTTTCCTATCTATGACATGCCttcattgaacaaagacttaccta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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