Basic Information
VIS ID
TVIS44015309
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
33644147/33070010 (Hg38)
End
33644147/33070010 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/8907506; hsa-mir-1267/Downstream/6594024;
Nearest TSS
ENST00000623511/Upstream/53577; ENST00000442716/Downstream/43183;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/52720, chr13-CpG: 88/Downstream/279783
Nearby gene
KL(+3865) ;
Nearest cancer related gene
KL(TSG, +3865) ;
Upstream sequence
GGAGAGCCCCAGAGTGGAGTAGTACCTCTGAATCTGCATGCTCTGGGATGTGCTGGCTAAATGCAGAAGACCAGGCCTTTTCCCCTCCCAGCCCACGCTT
Downstream sequence
TCGAAAGTGCCTTTGGGGGAAGATGGCGGCAGCACCCATGGCTTGGTAAGGGATCACTCCCGACTGATTCTGACACCCTGTTCATGGAGAACCACGGGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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