Basic Information
VIS ID
TVIS44015324
Fusion event
HTLV-1-AGO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
End
36337271/35871670 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-503-5p ; hsa-mir-148b-3p ; hsa-mir-130b-3p ; hsa-mir-106b-5p ; hsa-mir-107 ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-320c ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-151a-5p ; hsa-mir-93-3p ; hsa-mir-769-3p ; hsa-mir-421 ; hsa-mir-652-3p ; hsa-mir-628-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-146b-5p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-5p ; hsa-mir-326 ; hsa-mir-328-3p ; hsa-mir-330-3p ; hsa-mir-378a-3p ; hsa-mir-320a ; hsa-mir-195-5p ; hsa-mir-194-5p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-138-5p ; hsa-let-7g-5p ; hsa-mir-212-3p ; hsa-mir-34a-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-197-3p ; hsa-mir-106a-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-31-5p ; hsa-mir-29a-3p ; hsa-mir-26a-5p ; hsa-mir-25-3p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-let-7e-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3678-3p ; hsa-mir-4779 ; hsa-mir-2467-3p ; hsa-mir-19a-3p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-103a-3p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7i-5p ; hsa-mir-1-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-4684-5p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-942-5p ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-325 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-4632-5p ; hsa-mir-6735-5p ; hsa-mir-4436b-3p ; hsa-mir-100-3p ; hsa-mir-3166 ; hsa-mir-4756-3p ; hsa-mir-1324 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-8075 ; hsa-mir-219a-2-3p ; hsa-mir-218-5p ; hsa-mir-4266 ; hsa-mir-4717-5p ; hsa-mir-3919 ; hsa-mir-4695-5p ; hsa-mir-6510-5p ; hsa-mir-4690-5p ; hsa-mir-6165 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4279 ; hsa-mir-4777-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-892b ; hsa-mir-4514 ; hsa-mir-4524b-3p ; hsa-mir-4692
Nearest miRNA
hsa-mir-12136/Upstream/1201976; hsa-mir-101-1/Downstream/1289893;
Upstream sequence
TTAAAAACATGATTTTTAGTCTGGGTGTGGggtggcccatgcttgcaatcccagcactttgggaggccaaggtgggagaattgcttgagtccaggagttc
Downstream sequence
aagaccagcctgggcaacatagtaagactccatctctataaaTAAATAATGATTTTTGCCCTTTTCTTCTGTGAAAGAGCTGTAAATGACTTTTGCCTTA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate