Basic Information
VIS ID
TVIS44015335
Fusion event
HTLV-1-LOC105370259 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
74865532/74291395 (Hg38)
End
74865532/74291395 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13E
Target gene
LOC105370259
Nearest miRNA
hsa-mir-1297/Upstream/8073071; hsa-mir-1267/Downstream/3406617;
Nearest TSS
ENST00000623511/Upstream/59938; ENST00000423629/Downstream/127720;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/155714, chr13-CpG: 197/Downstream/1189321
Nearby gene
LINC00381(No orient, 127778)
Upstream sequence
TGCATGAGTTAGGAATTATTCAACTAACTGAAACATTCAAATAAATGTTCTGGTCAGCATGAGATGCAAGTGTGATTGGGAGGCCAGGAAGAAGTGTTGG
Downstream sequence
TAGTGATCTTAAGCTGAGGCTCAAAAGTCTCATCATCTGTGGTGGCAAGTGAGGCCCCAAGCATGGCTCTCTGGGCAAAGTCACATCCTCAGAGATATAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate