Basic Information
VIS ID
TVIS44015356
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
26896125/27038608 (Hg38)
End
26896125/27038608 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/1693134; hsa-mir-10400/Downstream/10245;
Nearest TSS
ENST00000518652/Upstream/171335; ENST00000521869/Downstream/47468;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/171559, chr8-CpG: 40/Downstream/249006
Nearby gene
ADRA1A(-173203) ;
Upstream sequence
gctgggattacaggcacccaccaccacaccaggctgatttttgtattttcagtagagacggggtttctccggtttctccacgttggccaggctggtctcg
Downstream sequence
tctttagtagagatggggtttctccatgttggccaggctgaactcctgacctcaagtgatccacccgccttagcctaccaaagtgctgagattacaggca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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