Basic Information
VIS ID
TVIS44015390
Fusion event
HTLV-1-LOC105374928 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
11449634/11449401 (Hg38)
End
11449634/11449401 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105374928
Nearest miRNA
hsa-mir-3691/Upstream/1009607; hsa-mir-10398/Downstream/4692155;
Nearest TSS
ENST00000381078/Upstream/32051; ENST00000423149/Downstream/37825;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/354967, chr6-CpG: 182/Downstream/87903
Nearby gene
NEDD9(-67053) ;
Upstream sequence
TTTTCCTAAGGACAGTCAAGATAAATATTGGCACTCTGAGTTCTCTCTGAGATCAAGTCAGTGCTCTCTGAGATCTCCCTGGTAGTGTAATGTAGAAATA
Downstream sequence
TGCCTTCCTCAGTCATCTCACAGGTAATTCTTGCCTCAGGAGAGATGTTAAGTTCCAGAAACATCACAATTGCGACTTGTAATAAGAATGAGAGAGTTTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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