Basic Information
VIS ID
TVIS44015408
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
6692361/6692362 (Hg38)
End
6692361/6692362 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3976/Upstream/317937; hsa-mir-1-2/Downstream/4067222;
Nearest TSS
ENST00000575820/Upstream/49884; ENST00000583410/Downstream/37356;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/277242, chr18-CpG: 63/Downstream/37241
Nearby gene
LINC01387(No orient, 101709)
Upstream sequence
GGGGAATGATAAAAGGGGGAAGCAAACGATTGCTTTTGTCTAGCTAATGGTCAGACAGGAGGAACCAGGACTAGGCAGGAGTGAATTTGCCGCCAGGGTA
Downstream sequence
GAAGTAGGTCAGTTGACAGCAATTTTCCAAACTAGCAGTTAGAACGTGGATAAATGCAAATGAACATGTCTGAACAATAATAGAGACTATTTGAAACTAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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