Basic Information
VIS ID
TVIS44015421
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
92892676/93637677 (Hg38)
End
92892676/93637677 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/7733970; hsa-mir-105-1/Downstream/1425464;
Nearest TSS
ENST00000429181/Upstream/1802172; ENST00000332647/Downstream/35891;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1855407, chrX-CpG: 20/Downstream/35870
Nearby gene
NAP1L3(-33249) ;
Upstream sequence
aatgacctgaaactggaaattatatttaaaagggaagccgagcattgatgtttggaaaatttgcagctggatatgtggtagaaaagaaaaacccatttcc
Downstream sequence
tggtgaggaattcaagccagctgcagaaatttgcataagtaaaggggagccaaaggtcattagccaggacaatggggaggcatcaaaggcatttcagaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate