Basic Information
VIS ID
TVIS44015422
Fusion event
HTLV-1-RGS7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
241078598/240915298 (Hg38)
End
241078598/240915298 (Hg38)
Orient
+
Location type
Intronic
Target gene
RGS7
Nearest miRNA
hsa-mir-101-1/Upstream/3444107; hsa-mir-3123/Downstream/216974;
Nearest TSS
ENST00000473358/Upstream/46503; ENST00000444330/Downstream/440478;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/91689, chr1-CpG: 104/Downstream/441341
Upstream sequence
agcccaacagactgagattatagcagagcctaaaccaccggggagtagggaaatatccaactccagcccctctatccttcccattgcacctaaagaggaa
Downstream sequence
aaacccccaaaacccaaggagcacatgtggagatcatggcccaggggtagaggctcactgtgggactgggtcctaatcatcagattatacaaagcatccc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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