Basic Information
VIS ID
TVIS44015450
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
16018248/15878124 (Hg38)
End
16018248/15878124 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3125/Upstream/3140680; hsa-mir-10b/Downstream/3470305;
Nearest TSS
ENST00000437798/Upstream/67247; ENST00000433810/Downstream/42275;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/285754, chr2-CpG: 220/Downstream/61555
Nearby gene
MYCNUT(No orient, 42273)
Upstream sequence
aggcacatgtatgtttattgcggcactactcacaatagcaaagacttggaaccaacccaaaggtccatcaatgatagactggattaagaaaatgtggcac
Downstream sequence
atatacaccatggaatactatgcagccataaaaaaggatgagttcatgtcctttatagggacatggatgaaggtggaaaccatcattctcagcaaactat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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