Basic Information
VIS ID
TVIS44015472
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
100311763/99846207 (Hg38)
End
100311763/99846207 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1E
Nearest miRNA
hsa-mir-101-1/Upstream/1800036; hsa-mir-11399/Downstream/435034;
Nearest TSS
ENST00000473358/Upstream/79576; ENST00000477753/Downstream/3877;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/581428, chr1-CpG: 63/Downstream/3657
Nearby gene
AGL(+3877) ;
Upstream sequence
CTAGATGTGACCCCTTCTTTTTtaaaaaaactattattaaaagtctatcatgtgctaagtgctagaatagatgcttcaaatgctttctttttttcttcta
Downstream sequence
atcttcatgccaaatttgcaagtgaggtcttgttctctccattttatgggtgatcaatcgtgattcagagtgattaaaacgaatccaaggtTTGTTTGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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