Basic Information
VIS ID
TVIS44015474
Fusion event
HTLV-1-ADD3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
111728208/109968450 (Hg38)
End
111728208/109968450 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ADD3-AS1
Nearest miRNA
hsa-mir-107/Upstream/5700045; hsa-mir-202/Downstream/929640;
Nearest TSS
ENST00000439456/Upstream/44897; ENST00000459738/Downstream/27918;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/44725, chr10-CpG: 123/Downstream/38879
Upstream sequence
GAAGCCTCCTTCCCATCCCAAAACAGCTACTGATTTCTTTTTCTTCAAAAAATGCTTATTAAAGGAGATAAATCTGTAGAACTCATTTCTAATTAAGCAG
Downstream sequence
GTAGCATCTTCCTTAACAATGTATTGTGGAGCTACTTCTATATCAGTACATTTGGGGAATTTTATAAAATTAAATGATGGTGATGATATATTATAGTTGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate