Basic Information
VIS ID
TVIS44015507
Fusion event
HTLV-1-CASC15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
21692933/21692702 (Hg38)
End
21692933/21692702 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
CASC15
Nearest miRNA
hsa-mir-3691/Upstream/3120822; hsa-mir-10398/Downstream/5454924;
Nearest TSS
ENST00000381078/Upstream/23883; ENST00000605917/Downstream/206018;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/26071, chr6-CpG: 100/Downstream/876653
Upstream sequence
AAAAAATTCCCCCAAAATACGAAAAACTGGCCCTTGCATTTTTTACGTTGCTCAATGTGGGTAACTGTTTAGTGGAAGTAGACATTCACTTAAATGGGGA
Downstream sequence
AAATGGAGAATGGACAATTCATTAAATGGAGGAAAATAAAGCCTTATTTTTTAAATGTTGCTGATAAAATATTTGGGTACTTAATGATGCTGAATCAAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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