Basic Information
VIS ID
TVIS44015524
Fusion event
HTLV-1-AP4B1-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
114425900/113883278 (Hg38)
End
114425900/113883278 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
AP4B1-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/1001149; hsa-mir-1182/Downstream/2676746;
Nearest TSS
ENST00000473358/Upstream/11519; ENST00000369563/Downstream/4027;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/70600, chr1-CpG: 61/Downstream/21554
Upstream sequence
ttctccattaaaagaaaccagaggccgggcgcagtggctcaggcctgtaatcccagtactttgggaggccaaagcaggcagatcacgaggtcaggagttc
Downstream sequence
aagaccagtctggccaacatagtgaaaccccgtctctactaaaaatacaaaaaattagctgggtgtggtggtatgcacctgtaatcccagctactcagga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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